The second artwork by Leonardo da Vinci, Mona Lisa is the greatest and most renowned art-piece of all time in the history. No other painting has gained fame and popularity as much as this single painting has gained in 500 years of its lifespan. Bearing the world-records of Most Imitated, most written about and most parodied work of art; it is the best-known portrait of all the time. The reason of its fame is the revolutionary work in its depiction and the “secret of the smile” of the woman. Every one’s baffling about if the woman is smiling or not. That’s the mystery. It is still unsolved. There is even a story about a French artist named Luc Maspero committed suicide leaving a note saying he preferred death after years of struggling to understand the mystery behind the woman’s smile. Any list for famous paintings is not complete without having this masterpiece.